SAF Nutrients: Turmeric

SAF Nutrients Turmeric

Turmeric is a wildly grown SAF plant native to southeast India known for its anti-inflammatory, anti-microbial and anti-neoplastic properties. Also known as curcuma longa (part of the ginger family), it is rich in SAF nutrients called curcuminoids, most notable among them is curcumin, which occurs in the rhizomes and roots. Curcumin consists about 3% of the dried turmeric powder.

Mechanisms of actions

Animal studies have shown that tumeric’s active ingredient curcumin interferes with key molecular pathways involved in cancer formation and metastasis. It has been reported to inhibit cancer-causing enzymes in rodents. Recent studies have shown that curcumin induces growth inhibiting effects and reduces development of several forms of cancer in lab animals. Human studies reveal that due to poor absorption curcumin needs to be taken in large dosages in order to reach the circulation. However, even though it has poor absorption to the blood circulation, curcumin has shown a greater absorption capacity into the colon lining and related cancerous tissues. A recent study revealed that curcumin supplementation reduced the incidence of abnormal crypt foci in smokers. Other studies indicate that turmeric (the whole plant) induces cholesterol lowering, anti-inflammatory and anti-ulceration effects. More studies are needed to elucidate the mechanism of actions behind turmeric (the whole plant) in general and curcumin in particular.

Properties

  • Chemo-protective (activates vitamin D receptor and mimics its chemo-preventing effects)
  • Anti-neoplastic (suppresses several stages of tumerogenesis by lowering concentrations of pro-carcinogenic substances in the colon and rectum; inhibits nuclear factor kappa B pathway in breast cancer cells and blocks metastasis)
  • Gastro-protective (protects against gastric ulcers via suppression of H2 histamin receptors)
  • Anti-inflammatory (inhibits the pro-inflammatory nuclear factor kappa B pathway; suppresses cyclooxygenase expression)
  • Vitamin D mimicking effects (mimics the stress response activities of vitamin D)
  • Anti-fungal, anti-bacterial (toxic effects of SAF nutrients in whole tumeric on pathological microbes)
  • Neuro protective (helps block plaques and formation of beta amyloid proteins in the brain that cause neuro-degenerative diseases)

Safety

More research is needed to find what is the safety threshold for turmeric and what is the potential risk for drug to drug interactions. Some people may be sensitive to turmeric, allergic reactions are possible.

SAF Stress-Response Complex

SAF Stress-Response Complex combines the most potent SAF nutrients specifically selected to mimic the effects of fasting and exercise on the body. These hard to find nutrients are specially sourced from barks, roots, rhizomes and leaves into one exclusive package. The formula includes berberine, salicin, green tea, resveratrol and turmeric to yield the right nutritional complexity at the right biological potency. Jump start your SAF experience with SAF Stress-Response Complex.

References

Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003;23:363-398.

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